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| Generic drugs news |
22.10.2011
Generics in the United Kingdom - Performance of the Market Is Forecast To Decelerate, With an Anticipated CAGR Of 7.9% for the Five-Year Period 2010... [reading]
22.10.2011
The US Generics Market Had Total Revenue of $71.4 Billion in 2010, Representing A CAGR Of 8.2% between 2006 and 2010 [reading]
21.10.2011
Antares Pharma Granted New U.S. Patent Covering VIBEX? Injector Technology [reading]
21.10.2011
Drugs giants probed by EU anti-trust authority [Deutsche Welle] [reading]
20.10.2011
CMS` Transparency Push Could Revolutionize Drug Pricing [reading]
19.10.2011
Perrigo confirms filing for generic version of PATANASE nasal spray [reading]
19.10.2011
Pharmacists to Federal Medicaid Officials: Revamp Proposed Generic Drug Federal Upper Limits to Preserve Pharmacy Access for Patients [reading]
19.10.2011
Teva Pharmaceutical Industries Ltd. and Cephalon, Inc.; Analysis of Agreement Containing Consent Orders To Aid Public Comment [reading]
18.10.2011
Perrigo applies to FDA for generic nasal spray [reading]
18.10.2011
Watson confirms filing ANDA for generic version of Warner`s Atelvia [reading]
18.10.2011
Watson confirms filing ANDA with FDA for generic version of Noven`s Daytrana [reading]
17.10.2011
New NCPA Ads Feature Community Pharmacy Proposals to Reduce the Federal Deficit [reading]
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Buy Celebrex |
| Home Page / Pain Relief / Celebrex |
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Celebrex (Celecoxib) is a nonsteroidal anti-inflammatory drug that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. |
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Product information |
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Drug Name: Celebrex (Celecoxib) Drug Uses: Celecoxib is used for the relief of pain, fever, swelling, and tenderness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib does not prevent the progression of either type of arthritis. It reduces only the symptoms and signs of arthritis. Celecoxib has been approved for patients with familial FAP who have not had their colons removed. Celebrex also is approved for the relief of acute pain and the pain of menstrual cramps (primary dysmenorrhea). How Taken: The lowest effective dose should be used for each patient. For the management of osteoarthritis, the dose usually is 100 mg twice daily or 200 mg as a single dose. For rheumatoid arthritis, the dose usually is 100 or 200 mg twice daily. For acute pain or menstrual cramps, the dose is 400 mg as a single dose on the first day, followed by an additional 200 mg if needed, then 200mg twice daily as needed. For FAP, the recommended dose is 400 mg twice daily. Drug Class and Mechanism Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat arthritis, pain, menstrual cramps, and colonic polyps. Prostaglandins are chemicals that are important contributors to the inflammation of arthritis that causes the pain, fever, swelling and tenderness. Celecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase 2), resulting in lower concentrations of prostaglandins. As a consequence, inflammation and its accompanying pain, fever, swelling and tenderness are reduced. Celecoxib differs from other NSAIDs in that it causes less inflammation and ulceration of the stomach and intestine (at least with short-term treatment) and does not interfere with the clotting of blood. NSAIDs have been found to prevent the formation and reduce the size of polyps in patients with the genetic disease, familial adenomatous polyposis (FAP). In FAP, patients develop large numbers of polyps in their colons, and the polyps invariably become malignant. The only cure of FAP requires removal of the entire colon. Celecoxib is approved as an adjunctive (secondary) treatment among patients with FAP. The cramping and pain during menstrual periods is due to prostaglandins, and blocking the production of prostaglandins with celecoxib reduces the cramps and pain. Missed Dose Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose as directed. Do not take a double dose of this medication unless your doctor directs otherwise. Storage Capsules should be stored at 25 degrees C (77 degrees F). It is okay for brief periods in temperatures between 15-30 degrees C (59-86 degrees F). |
Warnings/Precautions |
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There are no restrictions on food, beverages, or activity while taking celecoxib unless otherwise directed by your doctor. Concomitant use of celecoxib with aspirin or other NSAIDs (e.g., ibuprofen, naproxen, etc.) may increase the occurrence of stomach and intestinal ulcers. Fluconazole (Diflucan) increases the concentration of celecoxib in the body by inhibiting the breakdown of celecoxib in the liver. Therefore, treatment with celecoxib should be initiated at the lowest recommended doses in patients who are taking fluconazole. Celecoxib increases the concentration of lithium (Eskalith) in the blood by 17%. Therefore, lithium therapy should be closely monitored during and after therapy with celecoxib. Persons, taking the anticoagulant (blood thinner) warfarin (Coumadin), should have their blood tested when initiating or changing celecoxib treatment, particularly in the first few days, for any changes in the effects of the anticoagulant. Persons, who drink more than 3 alcoholic beverages per day, may be at increased risk of developing stomach ulcers when taking NSAIDs, and this also may be true with celecoxib. Celecoxib has not been studied in pregnant women. In animal studies, doses that were twice the maximally recommended dose were harmful to the fetus. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. The use of celecoxib in nursing mothers has not been evaluated.
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Possible Side Effects |
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Although stomach and intestinal ulcers occur with the use of celecoxib, their incidence is less than with other NSAIDs in short-term studies.
Celecoxib does not interfere with the function of the blood platelets and, as a result, does not reduce clotting and lead to increased bleeding like other NSAIDs.
The most common adverse effects are headache, abdominal pain, dyspepsia, diarrhea, nausea, flatulence and insomnia. Other side effects include fainting, kidney failure, heart failure, aggravation of hypertension, chest pain, ringing in the ears, deafness, stomach and intestinal ulcers, bleeding, blurred vision, anxiety, photosensitivity, weight gain, water retention, flu-like symptoms, drowsiness and weakness.
Allergic reactions can occur with celecoxib. Individuals who have developed allergic reactions (rash, itching, difficulty breathing) from sulfonamides (e.g., Bactrim), aspirin or other NSAIDs may experience an allergic reaction to celecoxib and should not take celecoxib.
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More Information |
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Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.
If you experience any of the following serious side effects, stop taking celecoxib and seek medical treatment or call your doctor immediately: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
Other, less serious side effects may be more likely to occur. Continue to take celecoxib and talk to your doctor if you experience flatulence or diarrhea; dizziness; headache; or insomnia.
Side effects, other than those listed here, may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
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| Help and FAQ |
What's the difference between generic drugs and brand-name drugs?
Actually, they both differ only in price and name, all the rest is the same. Generic drugs, as well as brand-name medications, have the same dosage, effects, including side effects, risks, strength and safety. They are like true copies of brand-name medications.
What makes generic drugs cheaper?
As a rule, in order to release and patent a certain drug the manufacturer should meet a range of requirements like developing, researching, marketing and promoting of a new medication. Overall, it is time- and money-consuming procedure, which leads to price growth. Speaking about generic drugs, they are usually brought unregistered onto the market, thus the manufacturer is exempt from paying taxes. However, the lower price here doesn't yield lower effectiveness. As a rule, the manufacturers of generic drugs are known reputable pharmaceutical companies.
What credit cards do you accept?
We accept Visa, MasterCard, AmEx, Diners and JCB cards.
Do you ship Internationally?
Yes, we ship Internationally at this time.
Order delay at customs: what to do?
It may happen that your order can be delayed at customs. In this case customs officers usually ask the recipient to come to the office and permit them to open a parcel in order to examine it. After this they give a parcel to the recipient. If you still have problems with getting your order, contact us so that we can help you solve this problem.
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